It was super easy for me. I think it really depends on what you are used to. When we had two kids, my husband was working two jobs and barely home. Both were majorly my responsibility. I was super nervous about 3, but the transition was SO simple.
However, for those used to their spouse taking one child while they take the other, 3 tends to be a bigger transition because now they have 2 to take care of.
Hope that makes sense. I always heard with 2 - dad takes one and mom takes one. So three is a majuor transition. But since with two, I already had both, three was simple.