Acanthosis nigricans is a skin disorder that results in velvety, light-brown-to-black markings that occur in areas including the neck, armpits, groin and under the breasts.
What Causes Acanthosis Nigricans?
Acanthosis nigricans can affect otherwise healthy people, or it can be associated with certain medical conditions. Sometimes acanthosis nigricans is congenital (something a person is born with). It also can occur as a result of obesity or an endocrine (glandular) disorder. It is frequently found in people with diabetes and is most common among people of African descent. There are many other possible causes of acanthosis nigricans, including:
Addison disease, a condition caused by a deficiency of hormones from the adrenal gland
Disorders of the pituitary gland within the brain
Growth hormone therapy
Hypothyroidism (low levels of thyroid hormone caused by decreased activity of the thyroid gland)
Answer by jaidah917 at 8:40 AM on Aug. 5, 2009
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