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Anyone decide against the progesterone shots? Why? If you decided to recieve it, why?

This is the shot giving to help reduce the chances of premature labor. I have tried googling it but it isn't helping me.

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Asked by kysmom642 at 9:55 AM on Aug. 27, 2010 in Pregnancy

Level 3 (26 Credits)
Answers (16)
  • I am anxious to see the answers. My DH and I are currently TTC, and because of difficulties I had when carrying my son, my OB-GYN is recommending that I do the progesterone shots.

    Answer by mommy11260 at 9:58 AM on Aug. 27, 2010

  • I took progesterone suppositories with all three of my successful pregnancies. I have had many miscarriages, I (and my doc) believe that the progesterone is what my body needed to keep the pregnancies safe.

    Answer by Scuba at 10:00 AM on Aug. 27, 2010

  • My daughter was born at week 32, 3 years ago. I have to take it every week until week 35. I don't want to have another premature birth so that is why I am taking them. I just can't seem to find a lot of information out there about them. My doctor said it was still being tested and I guess i missed that part because my husband told me that when we got home. I started to freak out.

    Comment by kysmom642 (original poster) at 10:05 AM on Aug. 27, 2010

  • My oldest son is 13, they have been using progesterone for quite a while! :) Talk to your doctor about what he meant, he should ease your mind.

    Answer by Scuba at 10:07 AM on Aug. 27, 2010

  • Thanks =)

    Comment by kysmom642 (original poster) at 10:08 AM on Aug. 27, 2010

  • My daughter took them for both her pregnancies. She was told her body doesn't make progesterone during pregnancies. Progesterone is what helps keep the pregnancy alive and growing. She had her first baby at 35.6 weeks. Her second at 28 weeks.

    Answer by MSugarKane at 10:20 AM on Aug. 27, 2010

  • I've never had this shot, but I also haven't gone into pre term labor. If I would have with my first or this pregnancy I think I would probably get it.

    Answer by cynprz at 10:23 AM on Aug. 27, 2010

  • i am curious about this as well. i have a preemie (33 weeks) & my midwife said they might do progesterone if i am pregnant again. i would definitely want to do something to prevent preterm birth because that was awful! but i would also want to know if it was safe and effective. from what i've read magnesium sulfate and terb aren't safe or effective, and procardia might work to stop labor for a day which would be good for the steroid shot. here is one link for progesterone

    Results. Seven randomized, controlled trials were identified. Women who received progesterone were statistically significantly less likely to give birth before 37 weeks (....)

    Answer by Stefanie83 at 12:00 PM on Aug. 27, 2010

  • and another


    Three trials were eligible for inclusion. There was a significant reduction in risk of delivery less than 37 weeks with progestational agents (relative risk [95% CI] = 0.57 [0.36-0.90]). There was no significant effect on perinatal mortality or serious neonatal morbidity.

    Progestational agents, initiated in the second trimester of pregnancy, may reduce the risk of delivery less than 37 weeks' gestation, among women at increased risk of spontaneous preterm birth, but the effect on neonatal outcome is uncertain. Larger randomized controlled trials are required to determine whether thi

    Answer by Stefanie83 at 12:01 PM on Aug. 27, 2010


    Prenatal administration of progesterone for preventing preterm birth in women considered to be at risk of preterm birth

    Babies who are born before 37 weeks, and particularly those born before 34 weeks, are at greater risk of suffering problems at birth. Progesterone is a hormone that inhibits the uterus from contracting and is involved in maintaining pregnancy. The review of eleven randomised controlled trials, involving a total of 2714 women and 3452 infants, found that where progesterone was given (by injection into the muscle in some studies and as a pessary into the vagina in others), there were some beneficial effects, including prolonging the pregnancy, but there is insufficient information about other possible benefits or harms. Further research is being undertaken.

    Answer by Stefanie83 at 12:02 PM on Aug. 27, 2010

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