depending on the strength...
5/500 - take one or two every 4-6 hours (this is vicodin)
7.5/750 -take one or two every 6-8 hours (vicodin ES and Lortab)
10/500 - take one every 6-8 hours (Lortab)
How it makes you feel -- it varies greatly from person to person. Some people get rather energized from them, and will get up and scrub the kitchen. Other people get very drowsy. If you don't know how it will affect you, take one when you don't have anything to do for a few hours. Don't drive.
Word to the wise - drink a glass of milk before you take one, or eat a light meal immediately after. (if you eat before you take it, the pill will sit on top of your food...essentially it will be last in line to get broken down and absorbed)
If you find you get extremely nauseated, you can crush the pill and mix it with a small amount of juice and take it like a shot. It won't hit your stomach so hard that way.
at 1:50 PM on Sep. 18, 2010