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How long does it take for Zoloft to kick in and start working?

I have been taking it for two days and I almost think its already working...

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Asked by Anonymous at 11:53 AM on Jul. 13, 2011 in Health

Answers (11)
  • Usually about a month for full effect.

    Answer by Musicmom80 at 11:54 AM on Jul. 13, 2011

  • It usually takes a good 2 weeks to start feeling any affects.

    Answer by twinsplus2more at 11:55 AM on Jul. 13, 2011

  • it usually takes a couple of weeks for the drug to really get in your system. Right now, it may be helping a little but most likely you are feeling better just knowing it will make you feel better.. if that makes any sense. It's the power of positive thinking :)

    Answer by alinker at 11:55 AM on Jul. 13, 2011

  • It takes about a month, right now the Zoloft is havign a Placebo affect.

    Answer by Zakysmommy at 11:57 AM on Jul. 13, 2011

  • I went through the same thing.... Like Alinker said, a lot of it has to do with your mind, knowing that help is on the way... Also, the dosage... I noticed a slight side affect every time the dose went up... it was a good one though... almost a "buzzed" feeling... kind of spacy, and giddy.... that didn't last long though... only a few days. The real help does kick in after about 4 weeks....

    Answer by mlivlee at 11:57 AM on Jul. 13, 2011

  • I actually changed to Pristiq because of that buzzing almost unreal fealing. But it takes 2 weeks to a month.

    Answer by Dardenella at 12:47 PM on Jul. 13, 2011

  • IF it is going to work, it will take some time for it to build up in your system. But all prescription antidepressants come with a price beyond dollars. 

    This group of drugs carries some of the most serious and frequently experienced side effects of any group of drugs in use; and most of the studies that are used to support their efficacy have been heavily challenged outside the US. Here, drug companies have such a strong lobby with government, and unethical power over the entities that are supposed to regulate them, that it is difficult to get reliable information about them. 

    In other countries, St John's Wort and SAMe (herbs and nutritional supplements) are routinely used for depression, with better results than ANY of the antidepressant drugs widely prescribed and advertised in the US.


    Answer by ss_mom at 1:33 PM on Jul. 13, 2011

  • ss_mom

    Answer by ss_mom at 1:34 PM on Jul. 13, 2011

  • 2 weeks to feel full effects. If you're already feeling better then that's great!

    Answer by DDWay at 7:42 PM on Jul. 13, 2011

  • Ever consider a natural alternative? Luminex is a patented formula of 3 ingredients that work naturally to maintain the health of your brain’s communication system.
    St. John’s wort to support neurotransmitters
    Griffonia seed to support neurotransmitters and to sustain a positive mood and emotionally stable outlook
    Vitamin B12 and folic acid to support the activities of brain messengers and to provide additional maintenance of neurotransmitters
    Chemical messengers ~ neurotransmitters in the brain affect your mood and your ability to cope. One of the most important messengers is the brain’s own mood-elevating neurotransmitter, serotonin. Luminex can give your body the tools it needs to maintain your ability to handle the stresses of life. Instead of resorting to chemicals or hormones to regulate mood. Luminex relies on a patented blend of natural ingredients that helps your body regulate itself gently & naturally.

    Answer by workin_at_home at 9:37 PM on Jul. 13, 2011

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