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Pilot Study: Urine Test Detects One-Third of Autism Cases via Psychcentral.com

Posted by on Apr. 25, 2012 at 11:49 AM
  • 5 Replies

Pilot Study: Urine Test Detects One-Third of Autism Cases

By TRACI PEDERSEN Associate News Editor
Reviewed by John M. Grohol, Psy.D. on April 25, 2012

Study: Urine Test Detects One-Third of Autism CasesA simple urine test detected one out of three children with autism spectrum disorder in a new study, and researchers say the test could result in earlier diagnosis and potentially lead to customized treatments for a subset of children with elevated levels of certain compounds in their urine.

The study included 76 boys from Oregon and Washington — 44 with an autism spectrum disorder and 32 without a developmental disorder.

Nick Heyer, a senior research scientist at Battelle’s Seattle lab, said he believes the research can be reproduced on a larger scale and hopefully lead to a widely available screening test for babies.

“If it can detect increased risk of autism at age 1, that would be fantastic,” he said. “It’s the only biomarker (test) I’m aware of that could be done noninvasively and fairly inexpensively. I’m really pretty optimistic and excited about getting it retested.”

Heyer said he is trying to incorporate the urine test into a study of 1,200 pregnant mothers who already have other autistic children. The study would follow the new infants’ development through age 3. He’s also working with a lab in South Korea to replicate the study in a larger group.

The urine test, which detects elevated levels of compounds called porphyrins, costs $50 to $100. Heyer said the test would become less expensive if used frequently as a way to screen babies.

James Woods, a researcher at the University of Washington who worked on the project with Battelle researchers, noted that everybody has the compounds in their urine, but the levels were clearly higher in certain children in the study. Also, although the study included only boys (who are much more likely to have autism than girls), Woods said that the test would likely work for both genders based on other research.

Heyer noted that although there’s been speculation that elevated porphyrin levels are related to mercury exposure in autistic children, the research team found no link to increased exposure to mercury. This leaves the question open of why the compounds are higher in some children with autism.

Source:  Batelle

http://psychcentral.com/news/2012/04/25/pilot-study-urine-test-detects-one-third-of-autism-cases/37791.html

by on Apr. 25, 2012 at 11:49 AM
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Replies (1-5):
RockinMama0608
by on Apr. 25, 2012 at 1:29 PM
1 mom liked this

I wonder if that would be a reliable test with a larger population.  Kind of interesting and would save time in diagnosing autism in children.

Austinsmom4544
by on Apr. 25, 2012 at 1:33 PM

That would be awesome if they could detect it at an earlier age :)


jeri.arellanes
by on Apr. 25, 2012 at 1:51 PM

Interesting.  I hope the test works.

steph2884
by on Apr. 25, 2012 at 3:00 PM

How strange. 

kajira
by Emma on Apr. 25, 2012 at 4:41 PM

I think it's interesting, but if it only detects 1 in 3 kids - does that mean that the genetic compenants, and other things would need to eventually be seperated into different categories?


like those who can show up on a urine test are a "different" thing, than those who have other genetic markers, vs those who have other disorders and show up in a different fashion? etc.

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