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Clomid & Soy Isoflavones (SERMs)

Posted by on Apr. 16, 2012 at 2:32 AM
  • 33 Replies
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Clomid (Clomiphene Citrate)

To understand why Clomid increases your chances of having twins, it is helpful to know how clomid works. Clomid works by blocking estrogen receptors in your brain. Estrogen is one hormone involved in the ovulation process. During the first part of your menstrual cycle, your estrogen levels are low (during menses). Normally, eggs begin to mature during this time and when this happens they produce estrogen. Estrogen levels increase as the eggs mature and eventually your estrogen levels reach a point that signals your body to produce another hormone known as LH. A surge in LH is what ultimately triggers ovulation.

Clomid is similar to estrogen in its make-up. It is a SERM (selective estrogen-receptor modulator). The receptor cells in your brain think that Clomid is estrogen which allows the Clomid to attach to the receptor cells. When Clomid attaches to the receptor cells, it keeps your own estrogen from attaching to the cells. This causes your body to think that you are not making enough estrogen. When estrogen levels are low, your body responds by making other hormones that help nurture and mature the follicles that are growing in your ovaries. Why you might ask? Because the follicles are what produce estrogen and your body wants your estrogen levels to increase. Your body thinks your follicles are not producing enough estrogen so it starts producing more of the hormones that help the follicles mature so that they will start producing more estrogen. Its a cycle.

The reason that Clomid increases your chances of having twins is fairly easy to understand. Your body is producing extra hormones to help your follicles grow and mature, thus increasing your estrogen levels. When this happens, a woman may have so much extra stimulation and nurturing that she produces more than one mature egg. If more than one egg is released during ovulation and both eggs are fertilized, twins will result. In most cases, Clomid twins are fraternal because they are the result of two different eggs.

What are the chances of having twins while taking Clomid?

You have about a 1-3 percent chance of conceiving twins naturally. Clomid does increase your chances of having twins, but not as much as you might think. You have about an 10-12% chance of conceiving twins while taking Clomid. For couples that have faced infertility though, the increased chance of having twins might not be a huge concern; actually, they might even see it as an added bonus.

Soy Isoflavones (SI)

What makes soy isoflavones similar to Clomid

Soy isoflavones are phytoestrogens known as SERMs, or Selective Estrogen Receptor Modulators. Clomid is also a SERM. Some people believe that soy isoflavones function in the same way to block estrogen receptors as Clomid.

Researchers have found that soy isoflavones bind to estrogen receptors. This evidence may support the idea that soy isoflavones can work as a natural ovulation inducer like Clomid.

 

by on Apr. 16, 2012 at 2:32 AM
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Replies (1-10):
luckymomma08
by on Apr. 16, 2012 at 2:52 AM

 where can you get soy isoflavones?

-Mommy-2-Three-
by Group Owner on Apr. 16, 2012 at 3:06 AM
luckymomma08
by on Apr. 16, 2012 at 3:10 AM

 thank you :)

Quoting -Mommy-2-Three-:

 

Quoting luckymomma08:

 where can you get soy isoflavones?

walmart, amazon, GNC, vitamin shoppe..........

http://www.amazon.com/Spring-Valley-Dietary-Supplement-Isoflavones/dp/B001R5Q9HA/ref=sr_1_1?ie=UTF8&qid=1334559796&sr=8-1

http://www.walmart.com/ip/Spring-Valley-Dietary-Supplement-Soy-Isoflavones-60-ct/10324815

http://www.gnc.com/product/index.jsp?productId=10886246

http://www.vitaminshoppe.com/store/en/browse/sku_detail.jsp?id=VS-1098 

BTW- soy isoflavones are about 1/2 as potent as clomid so 100mg of soy= 50mg of clomid (roughly)

 

 

-Mommy-2-Three-
by Group Owner on Apr. 16, 2012 at 3:20 AM

Taking it on CD1-5, 2-6 or 3-7 seems to have the highest twinning rates, as apposed to CD4-8 or 5-9!

Quoting luckymomma08:

 thank you :)

Quoting -Mommy-2-Three-:

 

Quoting luckymomma08:

 where can you get soy isoflavones?

walmart, amazon, GNC, vitamin shoppe..........

http://www.amazon.com/Spring-Valley-Dietary-Supplement-Isoflavones/dp/B001R5Q9HA/ref=sr_1_1?ie=UTF8&qid=1334559796&sr=8-1

http://www.walmart.com/ip/Spring-Valley-Dietary-Supplement-Soy-Isoflavones-60-ct/10324815

http://www.gnc.com/product/index.jsp?productId=10886246

http://www.vitaminshoppe.com/store/en/browse/sku_detail.jsp?id=VS-1098 

BTW- soy isoflavones are about 1/2 as potent as clomid so 100mg of soy= 50mg of clomid (roughly)

 

 

 

-Mommy-2-Three-
by Group Owner on Aug. 21, 2012 at 6:30 PM
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steph_twins
by New Member on Sep. 23, 2012 at 8:23 PM

so i have takin clomid, however i have a set of twins (natural twin preg) do you think my chances are higher? my youngest is a single..
we have twins on both sides....

-Mommy-2-Three-
by Group Owner on Sep. 23, 2012 at 8:25 PM

 

Quoting steph_twins:

so i have takin clomid, however i have a set of twins (natural twin preg) do you think my chances are higher? my youngest is a single..
we have twins on both sides....

Being on clomid raises chances from 2% to 10%, more if you have a family history or a previous twin pregnancy of your own :) Higher doses of clomid increase that chance even more obviously! 200mg would have a much higher risk of hyperovulation than 50mg.

steph_twins
by New Member on Sep. 23, 2012 at 8:31 PM

ugh oh! thats is how much i'm taking 200 mg. this is our 4th month!!
ugh i'm going to be so anxious to test..

Quoting -Mommy-2-Three-:

 

Quoting steph_twins:

so i have takin clomid, however i have a set of twins (natural twin preg) do you think my chances are higher? my youngest is a single..
we have twins on both sides....

Being on clomid raises chances from 2% to 10%, more if you have a family history or a previous twin pregnancy of your own :) Higher doses of clomid increase that chance even more obviously! 200mg would have a much higher risk of hyperovulation than 50mg.


emtmomtwo
by New Member on Oct. 16, 2012 at 4:31 PM

is it safe to try soy if i ovulate on my own? we have been ttc for close to three years. our kids are ages 5 and 6. we conceived them without a problem. my regular obgyn has run tests and everything has come back normal.

-Mommy-2-Three-
by Group Owner on Oct. 16, 2012 at 4:40 PM

Yes it is, it might make you O sooner too!!! GL hun

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