Karim Daniels, 9, was dropped off at Lizzie Rogers Park about 6 p.m. by a family member.
But when the family came to pick up the child about 7:30 p.m., he was gone, said Sgt. Jim Young, a police spokesman.
Karim stands about 4-foot-1, weighs approximately 75 pounds and was last seen wearing a white shirt, blue jeans and black sneakers.
Anyone with information about Karim's whereabouts can call Orlando Police at 321-235-5300.