An angel for everybody but me!

My little man was 2 on August 7th. I love him to pieces, but he can be so frustrating! We can't take him anywhere public without him screaming, throwing things, etc. He hates being confined (stroller, crib, etc.) and pitches a fit whenever he is strapped in. Even a quick meal in a fast food restaurant is difficult to get through. We've tried the usual...bringing toys, books, snacks- to no avail. He is also rather aggressive towards his older brother, but oddly enough, not towards his little toddler friends. The babysitter and even our own family says they haven't witnessed much of this. When he is put in time out in his room or another place, he destroys the area...emptying his bookcase or throwing his clothes around. He can be so difficult! We are not new to parenting, as we have a 5 year old who will be 6 in January.  It's crazy how different these two children are. I thought he was looking for attention, but he acts like this even when I've been home all summer with them (I'm a teacher.) I did spend his first year at home with him before returning to work (he was 13 months old when I did.) Any thoughts or suggestions on raising a difficult child? Maybe just terrible two's, but we don't know???