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Cochrane review says antibiotics for GBS not effective...

Posted by on Aug. 13, 2011 at 12:30 AM
  • 10 Replies

Group B Strep Treatment Questioned

Routine Antibiotics Given in Labor may not be Effective

IV Antibiotics Questioned for GBS - Anna Tankeh
IV Antibiotics Questioned for GBS -Anna Tankeh
A Cochrane review sheds doubt on whether or not routine antibiotics given to laboring mothers who test positive for GBS will reduce the risk of infection.

A common test for expectant mothers at about 36-37 weeks of pregnancy is known as Group B Streptococcal (GBS). GBS is a bacteria that often is found in the digestive tract, vagina and urinary tract with no symptoms in adults.

However 1 in 2,000 newborns become infected with GBS and due to their immature immune system, they can have difficulty fighting off the spread of this bacteria. If a baby becomes infected with GBS, it can cause respiratory disease, meningitis, sepsis (an infection that spreads throughout the body) and even death.

Routine Treatment of IV Antibiotics

If your GBS test comes back positive, your care provider will typically recommend that you begin IV antibiotic treatment as soon as you arrive at your place of birth. Many providers recommend a treatment that includes a dosage of ampicillin every 4 hours until the baby is born. The antibiotics are considered to be effective after four hours have passed from the first dose.

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However new evidence questions the effectiveness of routine antibiotics and in some cases, the treatment may even have negative effects.

Research Suggests that Antibiotics may not be Effective

A recent Cochrane review calls into question this routine practice to every mother testing positive for GBS. Their research indicates that when mothers were treated with antibiotics when they tested positive, it did decrease the risk of early GBS infection, but there was no difference in either late onset GBS or with neonatal sepsis between the groups who received IV antibiotics and those who did not. Antibiotics given in labor also did not decrease the incidence of newborn death.

Researchers point out that even if a GBS vaccine is developed, all cases of GBS related infections are not likely to be prevented.

(It is interesting to note that the researchers also suspect that the difference found in the early onset GBS was a result of bias in the studies that were a part of the review.)

Routine IV Antibiotics Can Cause Allergies and Yeast Infections

The downside is that treating all mothers with a positive GBS test with antibiotics during labor may cause other problems. One possible side effect is the potential for the mother to have an allergic reaction to the IV antibiotics. Not to mention, such early exposure of the baby to antibiotics can increase his or her problems with drug resistance later in life.

Another complication with antibiotic treatment is that it can cause mothers to develop yeast infections. Mothers and babies can then continue to pass persistent yeast infections back and forth through breastfeeding, known as thrush.

In summary, the reviewers found that, based on the studies they analyzed "giving antibiotics is not supported by conclusive evidence" as a routine treatment for GBS.

This is important information to share with your care provider when discussing your own birth plan especially if your GBS test comes back positive.



Read more at Suite101: Group B Strep Treatment Questioned: Routine Antibiotics Given in Labor may not be Effective | Suite101.com http://www.suite101.com/content/group-b-strep-treatment-questioned-a139897#ixzz1UscPQMjl
Posted by on Aug. 13, 2011 at 12:30 AM
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peaches_04
by Group Mod on Aug. 13, 2011 at 1:44 AM
I tested positive and didn't have the abx and lily was just fine
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One-n-Counting
by Group Mod on Aug. 13, 2011 at 1:48 AM
I never tested with ds2 and never received antibiotics. Im allergic To well over 6 antibiotics so the Risk isn't worth it for me.
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Pandapanda
by Gold Member on Aug. 14, 2011 at 1:28 AM
I wonder if breastfeeding immidiately after birth would lessen the odds of GBS related illness?
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peaches_04
by Group Mod on Aug. 14, 2011 at 1:29 AM
Hmm that's a good point

Quoting Pandapanda:

I wonder if breastfeeding immidiately after birth would lessen the odds of GBS related illness?
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truealaskanmom
by Gold Member on Aug. 14, 2011 at 1:33 AM
1 mom liked this


Quoting Pandapanda:

I wonder if breastfeeding immidiately after birth would lessen the odds of GBS related illness?

that and leaving the vernix intact and not bathing for a week or so 

malchusmom
by on Aug. 19, 2011 at 8:12 PM


Quoting peaches_04:

Hmm that's a good point

Quoting Pandapanda:

I wonder if breastfeeding immidiately after birth would lessen the odds of GBS related illness?

Definetly!!! I was told by my midwife that the sooner you start breastfeeding the baby the better and stronger the inmmune system will be to fight the bacteria and the baby will be just fine.

Mrs.Andrews
by Member on Aug. 19, 2011 at 8:26 PM

I just found out today I am negative! Thank God, I didn't want to deal with that battle since I am delivering in a hospital. I was positive with my first and received the antibiotics. She had persistent thrush and other yeast infections until she was 18 months old.

Sarah725
by Group Mod - Sarah on Aug. 19, 2011 at 9:52 PM
Wow bf is amazing. Im glad I was neg all 3 times.

Quoting malchusmom:



Quoting peaches_04:

Hmm that's a good point



Quoting Pandapanda:

I wonder if breastfeeding immidiately after birth would lessen the odds of GBS related illness?

Definetly!!! I was told by my midwife that the sooner you start breastfeeding the baby the better and stronger the inmmune system will be to fight the bacteria and the baby will be just fine.

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jconney80
by Group Mod on Aug. 19, 2011 at 11:25 PM
Thats interesting! Its good to know. My midwife wouldn't give me antibiotics even if I tested positive. I just took the test today at my backup Dr.
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Mama2lilGarrett
by Member on Aug. 21, 2011 at 10:50 PM

 Both times I have tested negative.

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