Will the stress in your life cause you to develop cancer? The answer
to this question may depend on what you eat according to a study
published in the August, 2008 edition of the International Journal of
Oncology.
Researchers examined the possible growth promoting
effects of the stress-associated hormone norepinephrine on immortalized
human pancreatic duct epithelial cells. The results suggested that
norepinephrine can increase proliferation of these cells. They then
evaluated the ability of norepinephrine to induce interleukin-6, and
vascular endothelial growth factor, both believed to promote cancer of
pancreatic duct epithelial cells. They found that norepinephrine can
indeed increase the interleukin-6 and vascular endothelial growth
factor in the cells.
Based on theses results, the researchers
performed further testing to see if dietary agents sulforaphane and
resveratrol can inhibit norepinephrine-mediated increases in cell
proliferation. Results indicated that sulforaphane but not resveratrol
inhibits the norepinephrine-mediated increases in cell proliferation.
Sulforaphane also inhibited norepinephrine-mediated increase of the
interleukin-6 levels of the cells.
We are living through an
extremely stressful period of history. Hundreds of studies have
documented how stress impacts our immune systems and ability to fight
off invading organisms. This study goes a long way toward documenting
the link between stress and cancer. The implications for further
research are huge.
Inhibiting norepinephrine is no small feat.
Norepinephrine is a neurotransmitter that is similar to adrenaline.
These hormones act together to produce heart rate and blood pressure
increases among other biochemical actions to launch us into our natural
defense mode, described as fight or flight. Chronic high levels of
stress result in chronic high levels of norepinephrine and adrenaline.
Sulforaphane
is a compound that can be obtained by eating cruciferous vegetables
such as Brussels sprouts, broccoli, cabbage, cauliflower, bok choy,
kale, collards, kohlrabi, mustard, turnip, radish, rocket, and
watercress.
The compound's anticancer activity is thought to be
related to the induction of phase-II enzymes such as quinone reductase
and glutathione S-transferase, and the enhanced transcription of tumor
suppressor proteins.
Sulforaphane is particularly abundant in
broccoli sprouts. Researchers at Johns Hopkins University School of
Medicine have been dedicated in their efforts to provide us with a
broccoli sprout that guarantees a consistent level of sulforaphane.
According to Johns Hopkins, eating just one ounce of their broccoli
sprouts provides as much sulforaphane as more than a pound of cooked
broccoli. Their product, called Brocco Sprouts, is available at many
traditional supermarkets.
If eating healthy amounts of
cruciferous vegetables does not appeal to you, try adding broccoli
sprouts to a sandwich or salad. Broccoli sprouts don't have to be eaten
daily to provide their full effect. A one ounce serving is good for
three days worth of full spectrum antioxidant protection from
sulforaphane comparable to the best antioxidant supplements on the
market. A box of sprouts contains four of these servings and retails
for about 4 dollars.
Juicing is another good way to consume
cruciferous vegetables, particularly if you have digestive
difficulties. You can add cruciferous vegetables to your vegetable
juice recipes. One large stalk of broccoli makes only about an inch of
power packed juice in a glass, so it doesn't have a huge impact on the
taste of the recipe.
Supplements of broccoli sprouts are
available at health food stores and online health retailers such as
Vitacost or Lucky Vitamin. The best known is called Broccoliv. Vitacost
has a less costly house brand.

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